Catalytic ozonation process using ZnO/Fe2O3 nanocomposite for efficient removal of captopril from aqueous solution

Volume 5, Issue 03, Pages 31-39, Sep 2022 *** Field: Analytical Method in Pharmaceutical Material

  • Maryam Dolatabadi Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.
  • Ruhollah Akbarpour MSc student in Environmental Engineering, Islamic Azad University, Estahban branch, Estahban, Iran
  • Saeid Ahmadzadeh, Corresponding Author, Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Keywords: Captopril, Catalytic ozonation, ZnO/Fe2O3 nanocomposite, Removal, Aqueous solution


The presence of pharmaceutical compounds in aqueous media, even in low concentrations, has caused adverse effects on human, animal, and environmental health. Captopril is a widely used pharmaceutical compound detected in the environment at different concentrations. Because of the concern and problems caused by the presence of captopril in water and the aquatic ecosystem, it appears necessary to remove it from the environment. The current study investigated captopril removal by a catalytic ozonation process using ZnO/Fe2O3 nanocomposite as a low-cost catalyst. The effects of variables such as ZnO/Fe2O3 nanocomposite dosage (0.5-2.5 g L-1), solution pH (3-11), initial captopril concentration (10-70 mg L-1), and ozone dosage (0.2-1.5 mg min-1) on captopril removal were investigated. The removal captopril of 99.4% was obtained in the optimum condition, including ZnO/Fe2O3 nanocomposite dosage of 2.0 g L-1, solution pH of 5.0, initial captopril concentration of 40 mg L-1, and ozone dosage of 0.5 mg min-1. The ZnO/Fe2O3 nanocomposite as a catalyst was a critical component in the catalytic ozonation process. According to the obtained results, the catalytic ozonation process in the presence of ZnO/Fe2O3 nanocomposite has high efficiency in removing captopril from water sources.


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How to Cite
Dolatabadi, M., Akbarpour, R., & Ahmadzadeh, S. (2022). Catalytic ozonation process using ZnO/Fe2O3 nanocomposite for efficient removal of captopril from aqueous solution. Analytical Methods in Environmental Chemistry Journal, 5(03), 31-39.
Original Article