A novel sorbent based on metal–organic framework for mercury separation from human serum samples by ultrasound assisted- ionic liquid-solid phase microextraction

Vol 2, Issue 03, Pages 67-78,*** Field: Analytical Chemistry in Human

  • *Negar Motakef Kazemi, Corresponding Author Islamic Azad University
Keywords: Metal–organic framework, Ultrasound assisted -micro-solid phase extraction, Mercury, Serum samples, Cold vapor atomic absorption spectrometry


In this research, the metal–organic framework (MOF) as a solid phase was used for separation mercury [Hg (II)] inhuman serum sample by ultrasound assisted- Ionic Liquid-solid phase microextraction procedure (USA- IL-μ-SPE). Mercury extracted from serum sample by [Zn2(BDC)2(DABCO)]n as MOF at pH=7.8. Hydrophobic ionic liquid ([BMIM] [PF6]) was used as solvent trap for Hg-MOF-NC from the sample solution. The phase of Hg-MOF-NC was back extracted by 0.5 mL of HNO3 (0.2 mol L-1) and finally mercury concentration determined with cold vapor-atomic absorption spectrometry (CV-AAS) after dilution with 0.5 mL of DW. Under the optimal conditions, the linear range, limit of detection and preconcentration factor were obtained 0.02–5.5 µg L−1, 6.5 ng L−1 and 9.8 for serum samples, respectively (%RSD<5%). The validation of methodology was confirmed by standard reference materials (SRM).


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How to Cite
Motakef Kazemi, *Negar. (2019). A novel sorbent based on metal–organic framework for mercury separation from human serum samples by ultrasound assisted- ionic liquid-solid phase microextraction. Analytical Methods in Environmental Chemistry Journal, 2(03), 67-78. https://doi.org/10.24200/amecj.v2.i03.68
Original Article