TY - JOUR AU - Abhijit De AU - S. Mojtaba Mostafavi PY - 2020/12/29 Y2 - 2024/03/19 TI - Sulfamethizole functionalized graphene oxide for in-vitro separation and determination lead in blood serum of battery manufactories workers by syringe filter-dispersive- micro solid phase extraction JF - Analytical Methods in Environmental Chemistry Journal JA - AMECJ VL - 3 IS - 04 SE - Original Article DO - 10.24200/amecj.v3.i04.124 UR - https://journal.amecj.com/index.php/AMECJ-01/article/view/124 AB - The toxic effect of lead (Pb) causes to anemia and iron deficiency in human body. So, the lead determination in blood/serum samples is very important.  In this study, a novel adsorbent based on sulfamethizole functionalized on nanographene oxide (C3H10N4O2S2-NGO; SM-NGO) was used for extraction of Pb(II) from human blood, serum and plasma samples in battery manufactories workers by SF-D-µ-SPE.  By procedure, 25 mg of SM-NGO mixed with 10 mL of human blood/serum or plasma samples and aspirated by 10 mL of syringe tube. After sonication of samples for 5 min, the Pb ions adsorbed based on sulfur of SM-NGO adsorbent at pH=6 and the solid phase separated by syringe coupled to Millex-FG hydrophobic PTFE membrane (0.2 µm). Then, the lead ions were back-extracted from SM-NGO/PTFE by elution phase with 0.5 mL of nitric acid solution (0.5 M). Finally, the concentrations of Pb(II) ions were determined by AT-FAAS.  ER -